THE SCIENCE BEHIND SOLPRANA™

Evidence-based nutrition tailored to the biological patterns seen in adults who use cannabis regularly.

Solprana’s formulations are built from three pillars:

  • Micronutrient Biology

  • Clinical Research

  • Endocannabinoid Pathway Understanding

Our goal is simple:
Support the systems that cannabis interacts with — so adults experience stability, clarity, and long-term wellness.

HOW CANNABIS AFFECTS NUTRIENT PATHWAYS

Nutrients Commonly Depleted or More Heavily Used:

OUR SCIENTIFIC FRAMEWORK

SCIENTIFIC PILLARS OF HAPPY HEALTH™

RESEARCH REFERENCES

Cannabis interacts with biological systems that regulate:

  • Stress hormones

  • Neurotransmitters

  • Inflammation

  • Mitochondrial energy

  • Antioxidant turnover

  • Methylation and B-vitamin cycles

Research and population studies show consistent patterns:

  • Magnesium

  • Folate (B9)

  • Vitamin B6 / B12

  • Antioxidants (C, E, ALA, NAC precursors)

  • Vitamin D

  • Zinc and copper balance

  • Omega-3 supportive pathways

Even mild insufficiency in these areas may lead to:

  • Daytime fog

  • Mood instability

  • Increased stress sensitivity

  • Disrupted sleep

  • Low energy

  • Muscle tightness

  • Inconsistent cannabis effects

These are not “cannabis problems” — they are nutrient demand problems.

Solprana applies a structured, evidence-based approach to supplementation.

1. Identify Nutrient Demand Patterns

We analyze:

  • NHANES population data

  • Oxidative stress studies

  • Cannabinoid metabolism research

  • Neurotransmitter + methylation pathways

  • Cardiovascular nutrient literature

2. Map Biological Overlap

We look for nutrient systems affected both by:

  • regular cannabis use

  • modern lifestyle patterns

The intersection reveals where support matters most.

3. Build Clinically Meaningful Formulations

Every ingredient in Happy Health:

  • has a defined nutritional role

  • comes in an effective form (bioavailable)

  • supports a documented pathway

  • avoids unnecessary additives

4. Independent Medical Oversight

Every formula is reviewed by:

Dr. Jeremy Dublon, DPM
Former FDA Medical Officer & Surgeon
Solprana Chief Medical Advisor

This ensures:

  • clinical alignment

  • safe nutrient levels

  • DSHEA compliance

  • scientific accuracy

  • no unintended interactions

Pillar 1 — Restore Core Nutrients

Magnesium bisglycinate, B-complex, methylated folate, vitamin D3, zinc/copper, vitamin E.

These support:

  • energy metabolism

  • neurotransmitter synthesis

  • cell repair

  • muscle + nerve stability

  • cardiovascular function

Pillar 2 — Antioxidant & Mitochondrial Support

Lion’s Mane, NAC, ALA, PQQ, selenium, milk thistle.

These support:

  • glutathione production

  • oxidative stress defenses

  • mitochondrial energy

  • brain + liver resilience

Pillar 3 — Long-Term Heart & Brain Support

  • Antioxidants

  • Omega-supportive pathways

  • Nervous system regulators

  • Nutrients tied to cardiovascular rhythm

Happy Health’s formula reflects this unified system, not isolated ingredients.

We align our formulation with evidence from:

  • NHANES Micronutrient Data

  • Center for Medicinal Cannabis Research

  • Oxidative Stress & Antioxidant Turnover Studies

  • Harvard School of Public Health

  • Nutritional Biochemistry Literature

  • Cardiovascular & Neurological Nutrition Research

We do not claim to diagnose or treat any disease.
We simply support biological systems that research shows cannabis interacts with.